Neuromuscular & Neurological Disorders in Chronic Kidney Disease: Expert Insights from Prof. (Dr.) Rohit Chhirolya MD, DM

Chronic Kidney Disease (CKD) is a progressive condition that not only affects kidney function but also leads to serious neurological and neuromuscular complications. These conditions arise due to uremic toxin accumulation, electrolyte imbalances, metabolic disturbances, and prolonged dialysis dependence.

This blog explores neuromuscular disorders, neurological complications, and bone-joint issues in CKD, along with specialized treatment approaches by Prof. (Dr.) Rohit Chhirolya, a leading neurologist in Cuttack, Odisha.

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Neuromuscular & Neurological Disorders in CKD

1. Uremic Neuropathy

• Cause: Nerve damage due to toxin accumulation in CKD.

• Symptoms: Burning pain, numbness, tingling, leg weakness.

• Treatment:

• Dialysis optimization for toxin removal.

• Neuromodulators: Gabapentin, pregabalin, duloxetine.

• Physiotherapy to prevent muscle atrophy.

2. Uremic Encephalopathy

• Cause: High uremic toxin levels affecting brain function.

• Symptoms: Confusion, memory loss, seizures, altered consciousness.

• Treatment:

• Emergency dialysis or hemofiltration.

• Electrolyte correction (sodium, potassium, calcium).

• Seizure management with anticonvulsants.

3. Dialysis-Associated Neuropathy

• Cause: Progressive nerve damage due to long-term dialysis.

• Symptoms: Sensory loss, weakness, muscle wasting.

• Treatment:

• More frequent dialysis or kidney transplantation.

• BP & diabetes control to slow progression.

4. Restless Legs Syndrome (RLS) in CKD

• Cause: Iron deficiency, dopamine imbalance, uremic toxins.

• Symptoms: Uncontrollable urge to move legs, worse at night.

• Treatment:

• Iron supplements, dopaminergic agents (pramipexole).

• Gabapentin or pregabalin for severe cases.

5. Osteosclerosis & Multiple Frozen Joints in CKD

• Cause: High parathyroid hormone (PTH) levels, dialysis-related amyloidosis.

• Symptoms: Bone pain, joint stiffness, fractures.

• Treatment:

• Phosphate binders & vitamin D therapy.

• Physical therapy for joint mobility.

• Surgical intervention in severe cases.

6. Uremic Myopathy

• Cause: Muscle atrophy due to uremia and metabolic imbalances.

• Symptoms: Progressive muscle weakness, fatigue, difficulty walking.

• Treatment:

• Protein intake optimization to maintain muscle mass.

• Metabolic acidosis correction with sodium bicarbonate.

• Exercise therapy to prevent muscle wasting.

7. Muscle Cramps in Dialysis Patients

• Cause: Fluid & electrolyte shifts during dialysis.

• Symptoms: Painful cramps, usually in legs.

• Treatment:

• Stretching before and after dialysis.

• IV saline or hypertonic glucose during dialysis.

• Magnesium supplementation if deficient.

8. Hypokalemia & Hyperkalemia-Related Muscle Weakness

• Cause: Severe potassium imbalances affecting muscle contraction.

• Symptoms:

• Hypokalemia: Muscle weakness, cramps, arrhythmias.

• Hyperkalemia: Muscle paralysis, cardiac risk.

• Treatment:

• Hypokalemia: Potassium supplements.

• Hyperkalemia: IV calcium, insulin with glucose, sodium bicarbonate.

9. Myasthenia Gravis in CKD (Rare, but Important to Recognize)

• Cause: Autoimmune attack on neuromuscular junctions.

• Symptoms: Muscle weakness, drooping eyelids, difficulty swallowing.

• Treatment:

• Cautious use of pyridostigmine (dose-adjusted in CKD).

• Plasmapheresis instead of immunosuppressants in advanced CKD.

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Expert Neurological Care for CKD Patients by Prof. (Dr.) Rohit Chhirolya

Why Choose Dr. Rohit Chhirolya for CKD-Related Neurological Disorders?

Prof. (Dr.) Rohit Chhirolya is a highly reputed neurologist in Cuttack, Odisha, specializing in the management of neurological complications in CKD patients. His expertise in handling uremic neuropathy, encephalopathy, restless legs syndrome, myopathy, and dialysis-related joint disorders has made him the top-referred neurologist by nephrologists, physicians, and dialysis centers.

His Specialized Treatment Approach

✔️ Personalized Dialysis-Neuro Management – Works closely with nephrologists to optimize dialysis schedules for better neurological outcomes.

✔️ Advanced Neuromodulation Therapy – Uses gabapentinoids, anticonvulsants, and dopaminergic agents tailored for CKD patients.

✔️ Electrolyte & Metabolic Correction – Ensures balanced potassium, sodium, calcium, and phosphorus levels to prevent muscle and nerve dysfunction.

✔️ Physical Rehabilitation Plans – Helps restore mobility in patients suffering from dialysis-related muscle and joint complications.

✔️ Pain Management in CKD Patients – Avoids nephrotoxic painkillers, ensuring kidney-friendly pain relief.

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World Kidney Day 2025: Honoring Dr. Amita Verma, MD, DM (Nephrologist)

On this World Kidney Day 2025, we extend our heartfelt appreciation to Dr. Amita Verma, MD, DM (Nephrologist) for her unwavering commitment to improving the lives of kidney patients. Through her comprehensive care and advanced dialysis protocols, Dr. Verma has been instrumental in:

• Optimizing dialysis regimens to reduce uremic toxin buildup.

• Maintaining balanced electrolytes to prevent severe muscle weakness and cramps.

• Collaborating with top neurologists like Prof. (Dr.) Rohit Chhirolya to manage complex CKD-related neurological disorders.

Her dedication ensures that CKD patients receive the best possible renal care, paving the way for improved quality of life and better neurological outcomes.

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Visit Prof. (Dr.) Rohit Chhirolya – Top Neurologist in Cuttack for CKD Neurological Care

• Clinic: Nilakantha Brain Clinic, KathaGola, Mangalabag, Cuttack

• Contact: 7985022365

Website:-

www.NilakanthaBrainClinic.com

For the best neurologist in Cuttack, Odisha, specializing in CKD-related neurological disorders, consult Prof. (Dr.) Rohit Chhirolya today!

Would you like to book an appointment or need expert advice? Let us know how we can assist you!